Monolithic Disc-based SPE Micro-Columns for Purification of Very Small Sample VolumesMonoSpin is an SPE column created by immobilizing a monolithic silica disc inside a microcentrifuge tube. The monolith disc disc is very rigid and requires no frits for immobilizing the column bed (unlike traditional SPE products), which allows essentially 100% recovery of the original sample volume after a couple of brief centrifugations.
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