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SPE Spin Centrifuge Columns
GL Sciences MonoSpin SPE spin columns provide improved concentration and yield for low-volume sample pre-treatment using centrifuge. MonoSpin features GL Sciences’ monolith silica technology with low-pressure, high-flow, and low-liquid-retention properties that allow for extraction with high recovery using smaller sample volumes compared to traditional particle media. MonoSpin columns are available in several formats for loading different sample volumes onto centrifuge. Read more
Octadecyl functional group. Optimal for drug extraction in biological samples, and desalting & enrichment of peptide samples.
For high viscosity samples, check out C18 FF which employs large through-pore monolith silica.
Specifications
Stationary phase: Octadecyl
Through-pore: 5 µm (S-type) / 10 µm (L-type) / 20 µm (S-type FF)
M...
From $220.00
Phenyl functional group. Optimal for the recovery of hydrophobic drugs in biological samples due to its weak retentivity and different selectivity compared to a C18 phase.
Specifications
Stationary phase: Phenyl
Through-pore: 5 µm
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 100 μg (Amitriptyline)
Available f...
From $240.00
Bounded with trimethylaminopropyl combining both strong anion exchange & weak hydrophobic interaction. Optimal for the extraction of acidic drugs.
Specifications
Stationary phase: Trimethylaminopropyl
Through-pore: 5 µm (S-type) / 10 µm (L-type)
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 100 μg (Ibuprofen)
...
From $220.00
Bounded with benzenesulfonic acid combining both strong cation exchange & hydrophobic interaction. Optimal for the extraction of basic drugs.
Specifications
Stationary phase: Propylbenzenesulfonic acid
Through-pore: 5 µm (S-type) / 10 µm (L-type)
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 100 μg (Amitriptyline...
From $220.00
Bounded with octadecyl and trimethylaminopropyl, a mix mode type. Delivers great retention for high salt concentrated serum samples. Optimal for the recovery of acidic drugs.
Specifications
Stationary phase: Octadecyl, Trimethylaminopropyl
Through-pore: 5 µm
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 100 μg (I...
From $240.00
Bounded with octadecyl and benzene sulfonic acid combining both ion exchange & hydrophobic interaction. Optimal for dissociated basic drug in biological samples. Delivers higher cleanup efficiency compound to C18 or SCX.
Specifications
Stationary phase: Octadecyl, Propylbenzenesulfonic acid
Through-pore: 5 µm
Mesopore: 10 nm
Surfac...
From $240.00
Bounded with carboxyl acid combining both weak cation exchange. Optimal for the extraction of basic drugs.
Specifications
Stationary phase: Carboxyl
Through-pore: 5 µm (S-type) / 10 µm (L-type)
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 100 μg (Amitriptyline)
Available formats: S-type spin column, L-type la...
From $240.00
Monolith skeleton coated with titanium dioxide. Excellent for the adsorption and removal of phospholipids.
Specifications
Stationary phase: Titanium dioxide
Through-pore: 20 µm
Mesopore: 15 nm
Surface area: 200 m2/g
Sample loading capacity: 40 μg (Adenosine monophosphate)
Available formats: S-type spin column
From $320.00
Bonded with iminodiacetic acid. Optimal for the recovery of trace metals.
Specifications
Stationary phase: Iminodiacetic acid
Through-pore: 5 µm (S-type) / 10 µm (L-type)
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 25 µg (Cu ions)
Available formats: S-type spin column, L-type large volume reservoir
From $270.00
Bounded with aminopropyl. Optimal for the enrichment of sugar chain and/or hydrophilic compounds by HILIC mode.
Specifications
Stationary phase: Aminopropyl
Through-pore: 5 µm (S-type) / 10 µm (L-type)
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 100 μg (Maltopentaose)
Available formats: S-type spin column, L...
From $220.00
Monolith skeleton coated with TiO2 and ZrO2. Excellent for the adsorption and removal of phospholipids.
Specifications
Stationary phase: Titanium dioxide, Zirconium dioxide
Through-pore: 5 µm (S-type) / 10 µm (L-type)
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 10 μL (Human serum)
Available formats: S-type s...
From $280.00
High selectivity columns with phenyl boronic acid. Optimal for selective extraction of cis diols, such as catecholamines.
Specifications
Stationary phase: Phenylboronic acid
Through-pore: 5 µm
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 100 μg (Dopamine)
Available formats: S-type spin column, 96-well plate
From $300.00
Bounded with amide. Optimal for the extraction of sugar chain chains and various hydrophilic acidic and basic compounds by HILIC mode.
Specifications
Stationary phase: Amide
Through-pore: 5 µm
Mesopore: 10 nm
Surface area: 350 m2/g
Sample loading capacity: 100 μg (Angiotensin II)
Available formats: S-type spin column, 96-well p...
From $240.00
SKU# 5010-21740
MonoSpin is a monolithic SPE column excellent for the small volume sample with an easy and quick operation by centrifuge.
Trial kits and custom kits are shipped with various types of columns packaged for initial method development.
This kit contains columns for C18, TiO, SCX, SAX, 10pcs of each. Optimal for drug extraction in biolog...
$220.00
SKU# 5010-21742
MonoSpin is a monolithic SPE column excellent for the small volume sample with an easy and quick operation by centrifuge.
Trial kits and custom kits are shipped with various types of columns packaged for initial method development.
This kit contains columns for SCX, SAX, CBA, NH2, 10pcs of each. Optimal for purification of ionic ana...
$220.00
SKU# 5010-21741
MonoSpin is a monolithic SPE column excellent for the small volume sample with an easy and quick operation by centrifuge.
Trial kits and custom kits are shipped with various types of columns packaged for initial method development.
This kit contains columns for C18, Amide, CBA, NH2, 10pcs of each. Compatible with both hydrophilic/h...
$220.00
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S Type spin column
L Type large volume reservoir spin column
96-well plate
- Disk size: 4.2 O.D. x 1.5 mm
- Sample volume: 50-800 µL
- Elution volume: 50-800 µL
- Centrifugation speed: 2,000-10,000 x g
- Disk size: 9 O.D. × 3 mm
- Sample volume: 0.5-8 mL
- Elution volume: 0.5-8 mL
- Centrifugation speed: 1,000 x g
- Disk size: 4.2 O.D × 1.5 mm
- Sample volume:～800 µL
- Elution volume: 100-800 µL
- Centrifugation speed: 2,000-10,000 x g (centrifuge; can also be used in vacuum aspiration)
Available Functional Groups for Spin Columns
How to choose Functional Groups
The MonoSpin series are optimized as a spin-column for pretreatment of biological samples. If you are working on highly viscous samples such as blood, MonoSpin C18 FF is the best choice. Please refer to the following chart for choosing appropriate MonoSpin:
MonoSpin Features
- Easy operation by centrifuge
- Speedy sample treatment with a superb through pore
- Excellent reproducibility (S-type) even at elution volumes of 100 μL or less
Silica Monolith packing material
New separation media that are neither particulate nor membrane
Silica monoliths are integral silica gels with uniform continuous pores synthesized from ethyl silicate. They have high liquid permeability and large surface area possessing a structure with through-pores and mesopores on the framework surface. This state-of-the-art media is becoming popular globally for its characteristics: high recovery and high performance of adsorption and desorption.
Advantages to conventional particle type packing
- Disk-shaped silica monoliths do not use frits to hold particle media
- The massive surface area of monolithic material makes it possible makes it possible to retain samples in the cartridge and completely elute small samples during processing allowing for much smaller volumes of sample needed.
- Despite high liquid permeability, silica monoliths are still suitable for rapid elution without the loss of high recovery with fast sample diffusion and quick separation.
How to Operate
Steps in Centrifugation for Spin Columns
Whole process for sample treatment can be done within 10 minutes.
Performance in analysis of trace analytes
Due to its high permeability, MonoSpin series enables collection of trace analytes without the need for dilution.
S type Column
L Type Column
