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C18 SPE Tip Columns for Trace Samples
The MonoTip C18 SPE pipette tip column contains silica monolith bonded with C18 (Octadecyl groups). Silica monolith has continuous through-pore structure. As C18 is bonded, MonoTip C18 can desalt and concentrate proteins and peptides in reversed phase mode by easy pipetting. Read more
Features
- Easy-to-Operate
- With MonoTip C18, samples are processed by pipetting. The operation is easier and less time consuming than using conventional SPE methods
- High efficiency with a wide range of molecular weights
- Continuous through-pore is the structural advantage of silica monolith, which enables MonoTip C18 to offer high efficiency. MonoTip C18 is available for peptide and protein samples with the concentration range from pmol to nmol
- A MonoTip C18 with a tip volume of 200 μL corresponding to a large volume sample and a MonoTip mini C18 with a volume of 10 μL corresponding to a trace sample were prepared.
- MonoTip C18
- Adapted to Peptide-Protein Samples with a Molecular Weight of Up to 40,000 in the Sample Concentration pico mol to nano molar order
Specifications
| Sample load capacity | 200 µL |
| Sample Treatment Concentration | pico mol to nano mol order |
| Sample Loading Concentration | 100 µg (AngiotensinII) |
| Tip Volume | 200 µL |
| Functional Group | Octadecyl |
| Organic solvent resistance | Acetonitrile 100% |
| Through-pore Diameter | 10 µm-20 µm |
| Meso-pores | 20 nm |
| Monolith | High Purity Zole – Gel Silica |
| Surface Area | 200 m2/g |
How to Use MonoTip C18 Tips
Applications
- Purifications of antihistamine in serum
- Hasegawa C et al., Rapid Commun. Mass Spectrom (2006);20:537-543
- “Simultaneous determination of ten antihistamine drugs in human plasma using pipette tip solid-phase extraction and gas chromatography / mass spectrometry”
- Purification of sulfatide (sulfoglycosphingolipid)
- Kyogashima M et al., Glycobiology (2006); 16(8),719-728
- “Rapid demonstration of diversity of sulfatide molecular species from biological materials by MALDI-TOF / MS
SPE C18 Tips Column for Trace Samples Resources:
- Download our entire 2022 Consumables Catalog — Download