MonoSpin

SPE Spin Centrifuge Columns

MonoSpin is a solid-phase extraction spin column that uses silica monoliths with uniform continuum pores. It effectively and rapidly extracts, isolates, purifies, and concentrates samples by centrifugation.

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Features

Highlights

Easy operation by centrifuge
Speedy sample treatment with a superb through pore
Excellent reproducibility (S-type) even at elution volumes of 100 μL or less

Silica Monolith packing material
New separation media that are neither particulate nor membrane

Silica monoliths are integral silica gels with uniform continuous pores synthesized from ethyl silicate. They have high liquid permeability and large surface area possessing a structure with through-pores and mesopores on the framework surface. This state-of-the-art media is becoming popular globally for its characteristics: high recovery and high performance of adsorption and desorption.

Advantages to conventional particle type packing

Disk-shaped silica monoliths do not use frits to hold particle media
The massive surface area of monolithic material makes it possible makes it possible to retain samples in the cartridge and completely elute small samples during processing allowing for much smaller volumes of sample needed.
Despite high liquid permeability, silica monoliths are still suitable for rapid elution without the loss of high recovery with fast sample diffusion and quick separation.

Products

Available Formats for Spin Columns

S Type spin column

Disk size: 4.2 O.D. x 1.5 mm
Sample volume: 50-800 µL
Elution volume: 50-800 µL
Centrifugation speed: 2,000-10,000 x g

L Type large volume reservoir spin column

Disk size: 9 O.D. × 3 mm
Sample volume: 0.5-8 mL
Elution volume: 0.5-8 mL
Centrifugation speed: 1,000 x g

96-well plate

Disk size: 4.2 O.D × 1.5 mm
Sample volume:～800 µL
Elution volume: 100-800 µL
Centrifugation speed: 2,000-10,000 x g (centrifuge; can also be used in vacuum aspiration)

Available Functional Groups for Spin Columns

Product	Functional Group	S/96 well Through pore (µm)	S/96 well Mesopore (nm)	L Type Through pore (µm)	L Type Mesopore (nm)	Surface Area (m²/g)	Bed Capacity (for type S)
MonoSpin C18	Octadecyl group	5	10	10	10	350	100 µg (amitriptyline)
MonoSpin C18 FF	Octadecyl group	20	15	10	10	300	50 µg (amitriptyline)
MonoSpin Ph	Phenyl group	5	10	-	-	350	100 µg (amitriptyline)
MonoSpin C18-AX	Octadecyl group, Quaternary ammonium	5	10	-	-	350	100 µg (ibuprofen)
MonoSpin C18-CX	Octadecyl group, Benzenesulfonic acid group	5	10	-	-	350	100 µg (amitriptyline)
MonoSpin SAX	Trimethylaminopropyl group	5	10	10	10	350	100 µg (ibuprofen)
MonoSpin SCX	Propylbenzenesulfonic acid group	5	10	10	10	350	100 µg (amitriptyline)
MonoSpin NH2	Aminopropyl group	5	10	10	10	350	100 µg (maltopentaose)
MonoSpin CBA	Carboxyl group	5	10	10	10	350	100 µg (amitriptyline)
MonoSpin Amide	Amide group	5	10	-	-	350	100 µg (angiotensin II)
MonoSpin PBA	Phenylboronic acids	5	10	-	-	350	100 µg (dopamine)
MonoSpin TiO	Titanium dioxide	20	15	-	-	350	40 µg (adenosine monophosphate)
MonoSpin Trypsin	Trypsin	5	10	-	-	350	-
MonoSpin ME	Iminodiacetic acid group	5	10	10	10	350	25 µg (Cu ions)
MonoSpin Phospholipid	Titanium dioxide, Zirconium dioxide	5	10	10	10	350	10 µL (human serum)
MonoSpin ProA	Protein A	2	60	-	-	-	400 µg (human IgG)
MonoSpin ProG	Protein G	2	60	-	-	-	400 µg (human IgG)

How to choose Functional Groups

The MonoSpin series are optimized as a spin-column for pretreatment of biological samples. If you are working on highly viscous samples such as blood, MonoSpin C18 FF is the best choice. Please refer to the following chart for choosing appropriate MonoSpin:

Discover the MonoSpin Series Lineup

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How To Operate

Short time centrifugation is used to pass the liquid in solid-phase extraction. The entire sample treatment process can be completed within 10 minutes.