Monolithic Silica Capillary HPLC Columns

GL Sciences’ MonoCap series, created synthetically via sol-gel method, and an octadecyl silane chemically bonded, has a very uniform three dimensional structure that shows excellent reproducibility from batch-to-batch. The solid structure of GL Sciences’ monolithic silica eliminates the need for frits or filters at the ends of the column, thereby reducing dead volume that might otherwise lead to band broadening or sample recovery. The high porosity of our monolithic silica allows high flow rates to be used without loss of resolution or creation of high operating pressure. An optimized balance of throughpores and mesopores provides the critically important combination of efficiency, separation speed, large volume sample-loading, and small volume sample-recovery.