As shown in Figure 1, InertSustainSwift C18 maintains the same extreme inertness, wide pH range and provide rapid separations with symmetric peaks. The optimization of surface area, pore size and chemical bonding delivers superior peak shapes (Figure 2). Figure 3 proves InertSustainSwift C18 is also ideal for LC/MS/MS applications which offer highly sensitive results and enables MS compatible buffers to be used due to the extremely inert silica gel.