The molecules of the target analytes pass through the fine pores in the particles in the packing material. Core-shell particles are formed around a solid non-porous core, resulting in less diffusion inside the fine pore structure. This differs from the more traditional fully porous particle. When using a core-shell column, the distribution of molecules in the peak is narrower when the target compound is eluted from the column, resulting in a greater number of theoretical plates.
The InertCore Plus C18 columns are subjected to rigorous internal quality control from bare silica manufacturing to inspection, resulting in superior reproducibility due to shell layer homogeneity.
InertCore Plus C18
Core-shell columns from other suppliers
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InertCore Plus C18 has high durability demonstrating that the performance for retention time, theoretical plate and symmetry factor is maintained even after 2000 continuous injections.
The results of analyses performed with the InertCore Plus C18 on two different HPLC systems, under the same conditions are shown. Peak shapes are excellent in both cases and equivalent chromatograms were obtained.
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InertCore Plus C18 Packed Guard Column, 2.6 µm, 20 x 2.1 mm, 1/Ea