InertSustain AX-C18 Anion Exchange Column has increased retention of acidic compounds/decreased retention of basic compounds compared to typical C18 columns.
Compounds:
1. Cytosine (basic) 2. Uracil (neutral) 3. CMP (acidic) 4. UMP (acidic) 5. Adenine (basic) 6. AMP (acidic)
No ion pair reagent in the eluent means highly polar acidic compounds are retained.
Strongly retains highly polar acidic compounds which normally cannot be retained by C18 columns for analysis of highly polar compounds!
InertSustain AX-C18 Anion Exchange Column strongly retains acidic compounds even if the salt concentration of the eluent is low. Also compatible with MS analysis.
Strongly retains highly polar acidic compounds even when salt concentration is as low as 10 mM! Sharp elution peaks!
Can be analyzed at low salt concentration. Compatibility with MS!
Reproducibility issues with mixed mode are solved by GL Sciences' original packing and manufacturing technology.
Excellent reproducibility of retention time in mixed‐mode columns where reproducibility is difficult to control!